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Novel mechanism for OSM-promoted extracellular matrix remodeling in breast cancer: LOXL2 upregulation and subsequent ECM alignment
SC Dinca, D Greiner, K Weidenfeld, L Bond, D Barkan, CL Jorcyk – Breast Cancer Research, 2021
Assessing a Novel 3D Assay System for Drug Screening against OS Metastasis
N Koons, N Amato, S Sauer, D Warshawsky, D Barkan, C Khanna – Pharmaceuticals, 2021
Innovative Approaches in the Battle Against Cancer Recurrence: Novel Strategies to Combat Dormant Disseminated Tumor Cells
S Sauer, DR Reed, M Ihnat, RE Hurst, D Warshawsky, D Barkan – Frontiers in Oncology, 2021
A small-molecule ARTS mimetic promotes apoptosis through degradation of both XIAP and Bcl-2
D Mamriev, R Abbas, FM Klingler, J Kagan, N Kfir, A Donald, … – Cell death & disease, 2020
Transcriptomic analysis of monocyte-derived non-phagocytic macrophages favors a role in limiting tissue repair and fibrosis
AA Butenko Sergei, Satyanarayanan Senthil K., Assi Simaan, Schif-Zuck Sagie … – Frontiers in Immunology, 2020
Dormant disseminated tumor cells and cancer stem/progenitor-like cells: similarities and opportunities
O Hen, D Barkan – Seminars in cancer biology, 2020
IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation
SK Satyanarayanan, D El Kebir, S Soboh, S Butenko… – Nature communications, 2019
Improved cancer drug development with drug disco
S Stewart, D Barkan, R Lampe, D Warshawsky… – Annals of Medical and Clinical Oncology, 2019
Osteosarcoma Metastasis: An Unmet Clinical Need and Unique Drug Development Opportunity
S Stewart, D Barkan, D Warshawsky, C Khanna – International Journal of Orthopedics, 2019
Soluble Mediators Produced by Pro-resolving Macrophages inhibit Angiogenesis
S Michaeli, V Dakwar, K Weidenfeld, O Granski… – Frontiers in immunology, 2018
EMT and Stemness in tumor dormancy and outgrowth: are they intertwined processes?
K Weidenfeld, D Barkan – Frontiers in oncology, 2018
‘Normalizing’ the malignant phenotype of luminal breast cancer cells via alpha (v) beta (3)-integrin
H Abu-Tayeh, K Weidenfeld, A Zhilin-Roth… – Cell death & disease, 2016
Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth
K Weidenfeld, S Schif-Zuck, H Abu-Tayeh, K Kang… – Oncotarget, 2016
β1-integrin: a potential therapeutic target in the battle against cancer recurrence
D Barkan, AF Chambers – Clinical Cancer Research, 2011
An in vitro system to study tumor dormancy and the switch to metastatic growth
D Barkan, JE Green – JoVE (Journal of Visualized Experiments), 2011
Metastatic growth from dormant cells induced by a col-I–enriched fibrotic environment
D Barkan, LH El Touny, AM Michalowski, JA Smith… – Cancer research, 2010
Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth
D Barkan, JE Green, AF Chambers – European journal of cancer, 2010
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton
D Barkan, H Kleinman, JL Simmons, H Asmussen… – Cancer research, 2008